A field experiment was conducted in a sandy loam soil at Zonal Agricultural Research Station, UAS, GKVK, Bengaluru to study the “Response of bio-digested liquid manure and different nutrient levels on growth and yield of barnyard millet under eastern dry zone of Karnataka” during kharif-2018. The test crop chosen was barnyard millet (DHBM 93-3) and the experiment was laid out in a randomized complete block design consisting of twelve treatments with three replications. The results of the experiment revealed that the application of N:P2O5:K2O at 30:20:20 kg ha-1 + FYM + BDLM on 35 DAS recorded significantly higher growth and yield attributes such as plant height, leaf area, total drymatter accumulation, number of tillers per plant, number of panicles per plant and 1000 grain weight (149 cm, 465 cm2 plant-1, 34.10 g plant-1, 8.2, 14.9 and 3.71, respectively) compared to all other treatments and significantly higher grain yield, stover yield and harvest index (2373 kg ha-1, 4297 kg ha-1 and 0.36, respectively) were recorded with application of N:P2O5:K2O at 30:20:20 kg ha-1 + FYM + BDLM on 35 DAS compared to rest of the treatments.